The article deals with the evaluation of sensorimotor responses with a view to professional selection. For a comprehensive assessment of functional potential of the nervous system we proposed the integral reaction parameter and modified method for determining of sensorimotor reaction time, which uses additional stress factors. Our study of the experimental group of athletes and the reference group of respondents shows that the difference between the result of standard and modified methods may be a criterion for human stress tolerance simultaneously evaluating the functionality of neuromotor system