Биомедицинская инженерия и электроника
Электронный научный журнал

Технические науки
EXAMINATION MODELING HEART FABRICS BIO
Novikova L.V. 1, Davidov A. 1

1. Kherson National Technical University

Abstract:

The work is devoted to modeling the excitation of biological tissues and the propagation of autowave oscillations along its surface. The analysis of occurrence of electric reverberators on the excited heart surface is carried out. It is shown that equipotential lines on one side are infinitely wound on the core of the reverberator of radius r0, on the other hand, they leave the nucleus with increasing pitch. The conditions shown when the reverb can and can not retain its spiral structure. It is determined that only 0.025% of the total energy of the action potential is enclosed in the electromagnetic field inside the fiber; the main energy is concentrated inside the membrane. The analysis of the phenomenon of fibrillation has shown that the violation often has the form of spiral auto-waves, reverberators. So far, reverb calculations are conducted mainly using two approaches. The first - the so-called kinematic approach - is of an exclusively general nature. The conclusion of the main integrated differential equation comes, basically, with geometric parcels. The biophysics of the process under the kinematic approach is taken into account rather weakly by the introduction of a small number of constant quantities: the critical value of the curvature of the front of the autowave, the speed of the plane front, etc. Such an important parameter as the shape of a wave of violations under the kinematic approach does not affect the calculation results. Another method of calculating reverb uses the differential equations of the parabolic type "reactiondiffusion", usually in a slightly simplistic form. At the heart of this direction is the model of HodgkinHuxley´s nerve tissue. Therefore, the main disadvantage of the Hodgkin-Huxley model (or D. Noble´s for the heart muscle) - the use of phenomenological dependencies of the conductivity of the membrane or the quantities associated with it, from the potential difference on the membrane - remains.

Keywords: simulation, bioassay, oscillation

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